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People with active cancer or history of cancer within 5 years should avoid use because growth factors and angiogenesis promotion could theoretically affect tumor growth

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What they did: Multiple preclinical models (mice, rats) evaluated the combination AOD-9604 + GLP-1 agonist (Semaglutide or Liraglutide)

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All authors have read and approved the final version of manuscript

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AOD-9604 Dosage for Bone Repair: Protocol Comparison | Protocol Type | Daily Dose | Injection Frequency | Duration | Bone Density Increase (Preclinical) | Optimal Use Case | Professional Assessment | ||||||| | Standard Repair | 300mcg | Once daily | 46 weeks | 1218% vs baseline | Acute fractures, post-surgical healing, moderate osteopenia | Gold standard

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