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CHAC1-mediated GSH degradation reduces S-glutathionylation of ARF6 at cysteine 90, thereby inactivating ARF6 and enhancing ferroptotic cell death ( Similarly, CHAC1 is upregulated in various kidney disease models (Ying et al., 2025)
An update on the molecular actions of fenofibrate and its clinical effects on diabetic retinopathy and other microvascular end points in patients with diabetes
doi: 10.1126/sciimmunol.aam6346 105 BonifaceKJacqueminCDarrigadeASDessartheBMartinsCBoukhedouniNet al
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extract on bacterial conjunctivitis model of Wistar rat caused by Streptococcus pneumoniae
(PubMed) Durga J, van Boxtel MP, Schouten EG, et al
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