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Because glycine is an amino acid naturally present in the body, there are relatively few absolute contraindications

Young adults balancing classes or early careers, parents, and adults 40+ with changing absorption often benefit

Thats because vitamin B12 is bound to protein and can only be released by digestive substances in the stomach (hydrochloric acid and gastric protease) to be absorbed

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For example, one study found that after taking 1,000 mcg of oral vitamin B12, only about 1.3% (13 mcg) is absorbed into the bloodstream