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Focused experiments conducted in rat striatum synaptosome preparations have reported that melatonin inhibits the excitatory response in a partially Ca 2+ -dependent manner in which the direct effect on membrane hyperpolarization promoted intracellular Ca 2+ influx reduction 94
The maximum activity of GPx was observed in exposed animals, pretreated with CRE-AgNPs, which corresponded to the availability of GSH in testicular cells
Uchida, H
[PubMed] [Wiley] Yang Y, Zeng Y, Yuan S, et al
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Studies of excess APAP-stimulated mouse and human primary hepatocytes have found very rapid, intense, and sustained activation of EGF receptor (EGFR) in the early stage of injury, which are possibly triggered by GSH depletion, after which levels of a series of toxicity markers begin to rise, and activation of EGFR signaling may contribute to late liver regeneration [247]
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