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According to NICE guidance, referral to a specialist may be appropriate for people with refractory gout despite urate-lowering therapy, those with tophi, where there is diagnostic uncertainty, or in the presence of significant kidney disease

The NanoString data have been deposited in NCBIs Gene Expression Omnibus (GEO) and are accessible through GEO Series accession number GSE218767

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At a medical spa, every injection is performed by a licensed providersuch as a nurse or nurse practitionerusing medical-grade supplies in a controlled environment

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