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Taking a break from an ADHD stimulant medication can partially reverse the physiological adaptive effects that result from chronic pharmacological stimulation and resensitize the neurons in the brain

Published trial protocols used 4-week escalation intervals, and deviating from this framework is the most common cause of poor tolerability in research settings

Understanding them in advance helps avoid delays and confusion

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This means: 1mL = 100 units 0.1mL = 10 units So, lets say your research protocol calls for a 250mcg dose