Weight loss mechanism: Much of the liver benefit likely comes through weight loss, which is highly effective for fatty liver disease
As diffusion across a membrane is a first order process, the transport rate is proportional to the solute concentration: r = k C , where C is the solute concentration and the constant of proportionality is the rate constant k
therefore, in rodents, GLP-1 induces satiety by its actions on caudal brainstem neurons
This can lead to side effects like sudden blood sugar spikes, increased hunger, and quick weight regain, potentially undoing much of the progress achieved during treatment
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Avasthi, A., Grover, S., & Sathyanarayana Rao, T