In addition to human activities such as use of agricultural pesticides, chemicals, coal-fired power plants, smelting, and mining, most of the As flux comes through natural sources including volcanic action, forest fires, erosion of rocks, and low-temperature volatilization (Neumann et al., 2010)
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GPX4, a selenocysteine-containing enzyme, utilizes GSH to reduce toxic phospholipid hydroperoxides (PL-OOHs) to non-toxic phospholipid alcohols (PL-OHs), thereby disrupting lipid peroxidation chain reactions and preventing oxidative cell injury (Pontel et al., 2022)
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B12 helps produce the amino acid tryptophan, which is a big part of what makes us fall asleep at night
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