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The skin-lightening effect mainly occurs due to the inactivation of the enzyme Tyrosinase, which activates the melanin pigment
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Winter SC, Szabo-Aczel S, Curry CJ, Hutchinson HT, Hogue R, Shug A: Plasma carnitine deficiency
However, LAC combined with clozapine was found to not significantly improve the treatment effect of schizophrenic patients who were tolerant to clozapine (73) (Studies are summarized in Table 4)