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Fecal microbiota transplantation from patients with Parkinsons disease into germ-free mice has been shown to reproduce aspects of motor dysfunction and inflammatory responses, supporting an association between gut microbiota alterations and disease-related phenotypes [59]
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Importantly, classifiers constructed on functional metagenomic characteristics (e.g., butyrate synthesis pathways, LPS biosynthesis genes) outperformed those based merely on taxonomy [188]
Nat Rev Endocrinol 20(11):647660 Dosiou C, Kossler AL (2021) Thyroid eye disease: navigating the new treatment landscape
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