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Semaglutide acts on GLP-1 receptors in the brain's appetite centers, particularly the hypothalamus, to reduce hunger and increase feelings of fullness

A programme of phase 3 trials with retatrutide (TRIUMPH) is ongoing with an aim to assess the safety and efficacy of retatrutide in different populations living with obesity (OSA, T2D, established cardiovascular disease, osteoarthritis)

Making an informed choice requires understanding exactly what those differences mean for your treatment experience

No change at all

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& Doolittle, R