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Konopka P, Janucik A, Citko A, Paszko A, Kretowski AJ, Szczerbinski

Data was weighted to be nationally representative across age, gender, region, race, and ethnicity (using the latest publicly available US Ccnsus numbers)

In rabbits, doses up to 0.072 mg/kg/day, which is approximately 1-time the maximum recommended human subcutaneous dose of 60 units/day (0.0364 mg/kg/day), based on mg/m2, were administered during organogenesis

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This has led to interest in its possible use in treating nerve injuries

Some highly sensitive receptor binding assays may require even higher purity to avoid interference from peptide-related impurities