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Wang IY et al
, J Med Chem 60(12):5015-5028 , USA , 2017 Q1 Screening of over a thousand NNMT-inhibitor analogues on a quinolinium scaffold identified compounds ranging from nanomolar to millimolar IC50 - a greater than 1000-fold spread of potency across the series
The medicine targets the brain and mimics that full feeling, plus reduces appetite, slows stomach emptying and ultimately decreases your caloric intake
Kagabu S et al
Reduced oxygenation shows up as paleness, a sallow or washed-out complexion, and slower wound healing
