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Last reviewed: May 30, 2026 Last updated: May 30, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Gastrointestinal side effects peak during dose escalation but begin to stabilize

Not effective for individuals with severe deficiencies

Interestingly, low blood levels of vitamin B12 have been linked with reduced bone mass, though clinical trials have not definitively supported the efficacy of B vitamin supplements in treating fractures ( Recent research states that the role of vitamin B12 and bone health is not well established

Dosing What is the standard GLOW dose

It's not a furnace blast