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FOXO6, as the most evolutionarily divergent member of this group, exhibits tissue-specific expression, particularly in liver, muscle, and neural tissues, and its effects on insulin signaling significantly differ from the other isoforms

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Moreover, cystic fibrosis, idiopathic pulmonary fibrosis, and COPD also have elevated oxidative stress and inflammation levels in common, both of which could be attenuated with NAC ( 23 )