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doi: 10.1016/j.ncl.2021.01.009 [PubMed] 34221552 Kirmani BF, Au K, Ayari L, John M, Shetty P, Delorenzo RJ

Less frequent dosing: Only one shot per week

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That designation requires FDA-registered manufacturing facilities, validated processes, and regulatory oversight that research chemical companies do not have

For patients with type 2 diabetes, GLP-1 medications are generally considered long-term therapy as part of individualized disease management

Over time, metformins ability to treat insulin resistance without weight gain or increased risk of hypoglycemia was recognized, and it was introduced to the US in 1995