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In DKD, upregulation of local angiotensin II in the renal tubule, activation of vascular endothelial growth factor (VEGF), and reduction of nitric oxide (NO) (60) can lead to constriction of both the afferent and efferent arterioles, as well as the interlobular arteries, compromising blood flow regulation

7 Discussion This study shows a first comparison of kinetics and molecular properties of different e-GSTs from mammalian species

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cConcentration of the analyte in the final sample solution, in micrograms per milliliter (g/mL)

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