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Preclinical and emerging cohort data suggests GLP-1s modulate the brains reward pathways , effectively quelling not just hunger but the impulse to intoxicate. Heinekens 2025 total volume declined 1.2% as global demand softened amid shifting consumer trends.The decline was steepest in Europe (-3.4%) and the Americas (-2.8%) , where consumer price sensitivity and shifting health trends hit hardest

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