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The main intracellular producer of ROS and RNS is the mitochondrial respiratory chain (Ray et al., 2012) and the increase of oxidative damage or release of mitochondrial DNA observed during mitochondrial dysfunction act as danger-associated signals (DAMPs), which initiate the immune response through pro-inflammatory NF-B activation (Picca et al., 2020)

The damage is irreversible

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Jama 314 , 16371638 (2015)

Cancer progression due to hyperglycemia was reported in multiple cancers, including breast, colorectal, brain, and pancreatic cancer [22,23,24,25]

Enhance Recovery and Athletic Performance L-Carnitine is widely recognized for its ability to improve athletic performance and accelerate recovery