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[2] The safety profile of Orforglipron was consistent with existing GLP-1 therapies, with the most common adverse events being mild to moderate gastrointestinal symptoms such as diarrhea, nausea, dyspepsia, and constipation

M.et al (2020a)

A group of compounds, termed mitocans, which target the mitochondrial structural integrity and respiratory and thiol redox functions, are being studied extensively, as they have a potential to be effective therapeutic drugs against cancer [20], [21], [22]

Nonfatal stroke is a leading cause of disability worldwide, with high costs of medical care and a major impact on patients quality of life [63]