SIRT1 is part of a family of proteins called sirtuins, known as longevity genes. It uses NAD+ as a fuel source to repair DNA, reduce inflammation, and improve stress resistance
It aids in the removal of toxins and heavy metals, which can otherwise impair immune function
In general, dermatologists recommend 600-1200 mg glutathione per dose through the IV route, but the exact quantity varies for every person
L-Arginine is sometimes used as a similar supplement, however L-Citrulline is more bioavailable, easier on the digestive system, more effective and has a longer-lasting effect
Mathers et al., 1997, 2018
Oral supplements offer convenient daily administration with various formulation options, though they typically show gradual absorption rates