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Misfolded -synuclein can be released extracellularly, activating microglia and spreading pathogenic seeds or DAMPs to neighboring neurons, amplifying degeneration

These symptoms are usually mild and improve with adequate sleep, hydration, and eating nutrient-dense foods when appetite permits

Tell all your healthcare providers that you are taking Saxenda before you are scheduled to have surgery or other procedures Saxenda may cause serious side effects, including: The most common side effects of Saxenda in adults include nausea, diarrhea, constipation, vomiting, injection site reaction, low blood sugar (hypoglycemia), headache, tiredness (fatigue), dizziness, stomach pain, and change in enzyme (lipase) levels in your blood

The majority of patients (86%) had diabetes, and all had a Hidradenitis Suppurativa Physicians Global Assessment (HS-PGA) score of 1 or higher

Ultimately, open and informed dialogue between patients and their healthcare team remains the cornerstone of safe prescribing