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J Mater Sci 57:1901919049 Jiang X-R, Mi J, Wang Y, Yin M, Tong Y, Zhu Y (2025) Application of metal-organic frameworks nanoparticles in the diagnosis and treatment of breast cancer

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Longer-term continuous use (6+ months) has less established safety data, though no significant concerns have emerged

That doesn't make it reckless if you're monitoring appropriately, but it does mean the risk-benefit calculation is yours to make with incomplete information

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Micropenis: Does early treatment with testosterone do more harm than good