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But I also prescribe medications like semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound) for weight loss

Evidence indicates that GLP-1RAs confer substantial cardiovascular and renal benefits

Zhao TC, Taher MM, Valerie KC, Kukreja RC: p38 Triggers late preconditioning elicited by anisomycin in heart: involvement of NF-kappaB and iNOS

Candidates for Treatment With SGLT2 Inhibitors or GLP-1 Receptor Agonists In general, SGLT2 inhibitors are recommended for patients with established ASCVD or HF who do not reach appropriate glycemic goals through treatment with metformin and lifestyle modifications

Final thought Kelly Clarksons weight loss appears to be the result of walking more, eating cleaner, and working with her doctor to stay on top of her health

Diarrhea In consistency with the previous safety outcomes, diarrhea was more frequent in the GLP-1 receptor agonists group (Fig