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As stated in FDA prescribing information, semaglutide should not be restarted after a confirmed pancreatitis episode, and alternative diabetes or weight management strategies should be pursued

GLP-1RA as an independent class of drug is also noteworthy in reduction of weight in patients with and without poor glycaemic control with multiple trials backing the efficacy of agents including semaglutide and liraglutide (116)

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doi:10.1210/clinem/dgz140 Grandone A, Di Sessa A, Umano GR, Toraldo R, Miraglia Del Giudice E

After swallowing the tablet whole (not split, crushed, or chewed), patients must wait at least 30 minutes before eating, drinking anything other than water, or taking other oral medications