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GLP-1 Drugs: The Strongest Path to Lasting Weight Loss & Improvement in Related Health Conditions September 12, 2025 By: Janet Klein, MS, RDN, CDN, CDCES Categories: Bariatric, Blog, Health & Wellness Janet Klein, MS RDN, CDN, CDCES, Bariatric Surgery and Obesity Medicine Program Director It may not be much of a surprise to hear that with the increased use of GLP-1s for weight loss, there has been a noted decline in patients undergoing bariatric surgery

On the gastrointestinal front, literature has described mucosal barrier protection via modulation of endogenous prostaglandin (PGE2) and heat shock proteins (HSP70/90)

Glyceric and glycolic acids are elevated in hyperoxaluria.[ref]

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Thankfully, focusing on a few simple strategies, such as adding protein to each plate, staying hydrated, and practicing mindful eating can allow you to show up feeling confident, stay consistent with your goals, and still fully enjoy all the experiences summer can offer

With that being said, the patients that lose the most weight are those that make meaningful lifestyle changes