Erythromycin counteracted the effect of GLP1 on the velocity of gastric emptying and lowered the post-prandial anti-hyperglycemic effect of GLP1
doi: 10.1016/J.FREERADBIOMED.2018.08.007 38 HeijinkIHvan OosterhoutAJM
Her provider started Rybelsus, carefully explaining the strict morning routine: take on truly empty stomach, wait full 30 minutes before coffee or food
At the same time, her hair was falling out, she was constantly depleted of energy, she had irregular cycles, and she felt generally not right. But within a year of starting on Mounjaro, not only did she lose about 100 pounds (and reach a healthy weight for her), but her PCOS symptoms let up, her A1C went down, and the clarity in my mind came back, she says
doi: 10.1210/jc.2016-2660 26 AnJKimYKimKKimSKimNKimHet al
A central insight emerging from the GLP-1 experience is that biological pleiotropy does not preclude therapeutic utility