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doi: 10.1016/j.tplants.2011.09.005 105 GaoC

During tumor progression, emerging evidence links ROS to survival and growth signaling pathways, such as those involving the HIF-1/VEGF axis, JAK/STAT3, and AKT/mTOR, which can strengthen phenotypes related to cell proliferation, anti-apoptosis, and angiogenesis