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However, tirzepatide is not FDA-approved for treating MASLD, and any such use would be considered off-label
is supported by funds from the Ministry of Education and Science of Poland within the project 'Excellence Initiative - Research University', the Ministry of Health of Poland within the project 'Center of Artificial Intelligence in Medicine at the Medical University of Bialystok', the Medical Research Agency within the project 'Regional Center for Digital Medicine at the Medical University of Bialystok' (grant number 2023/ABM/02/00008), and the American Diabetes Association grant 11-22-PDFPM-03
What is unknown about GLP-1 drug use is as important as what is known
Nyberg J, Anderson MF, Meister B et al (2005) Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation
[7] Effectiveness and Key Trials: The rapid uptake of GLP-1 receptor agonists is largely driven by their consistent and clinically meaningful benefits across multiple large randomized trials
Phentermine is not a GLP-1 and does not work through the same pathway
