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Cytokine storm or CRS, a clinical state of hyper-inflammation, is a prominent feature of COVID-19 severity, linked to respiratory dysfunction, ARDS with adverse disease outcomes 220,221

Many clinicians and researchers extend the time at each dose level if side effects are bothersome

Addressing sleep quality and stress load before and during the taper, rather than planning to get to it later, meaningfully affects how hungry you feel and how well your metabolic rate holds after stopping

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For others, especially those managing significant oxidative stress, following a detox protocol, or preparing for pregnancy, demand can outpace what diet and lifestyle alone can replenish