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doi: 10.1007/S12020-021-02945-1 57 KatoleNTSalankarHVKhadeAMKaleJSBankarNJGosaviPet al

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Fenofibrate slows DR progression and may influence retinal lipid signaling beyond lipid lowering

The Utah Early Neuropathy Scale (UENS) focuses on small-fiber signs and pinprick testing, showing sensitivity of 78% and specificity of 85%, while the DN4 questionnaire targets neuropathic pain features with 83% sensitivity and 90% specificity, exceeding the NDS for painpredominant presentations (see Table 4)

Maresin-1 inhibits high glucose induced ferroptosis in ARPE-19 cells by activating the Nrf2/HO-1/GPX4 pathway