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Several studies suggest that the renal proximal tubule (PT) plays a critical role in CKD

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Moreover, in a lean mouse model of severe nonalcoholic fatty liver disease, phosphatidylethanolamine N-methyltransferase mice, we observed a 4-fold increase in circulating DPP4, in contrast with previous findings connecting DPP4 release and obesity

doi:10.1007/s00702-018-1952-7