Other symptoms of B12 deficiency include pale skin, loss of appetite, heart palpitations, unexplained weight loss, depression, poor memory, confusion, and soreness of the mouth or tongue
Theoretical concerns are not proof of harm, but they identify areas off-target SAM effects, signalling-pathway impacts, and uncharacterised interactions that require study before any conclusion about human safety could be drawn
PMC 374312
Vitamin B12 Deficiency The exact prevalence of Vitamin B12 deficiency remains unknown, but recent studies estimate between 1% and 20% of American adults have lower than optimal levels
Appetite stimulation : Some patients may experience increased appetite, which we can help manage through our personalized nutrition plans
A minimum of two months must pass between doses