semaglutide for crohn's & Disease: Safety & IBD Considerations – PlexusDx semaglutide colon issues GLP-1 use

Genetic predispositions to insulin resistance (variants in GIPR genes) and elevated FTO-associated weight gain risk may provide additional clinical context

Anaphylaxis, while extremely uncommon, requires immediate emergency medical attention

Also, cerebrovascular insufficiency can be associated with changes in behavior, such as apathy (loss of interest), anxiety, or depression

While there is no absolute contraindication to tirzepatide use in autoimmune disease, several safety considerations warrant attention

This can considerably influence organ toxicity for instance in the heart, liver and kidney

doi: 10.1038/oby.2000.32 110 KarlssonCLindellKOttossonMSjstrmLCarlssonBCarlssonLMS