Veterans Affairs Cooperative Study and Prospective European Doxazosin group evaluated the combination of finasteride with terazosin & doxazosin, respectively for one year
However, metabolic changes and weight loss take time
Its often included in advanced biohacking protocols alongside magnesium, nootropics, mitochondrial support supplements, and adaptogens
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ALS can also be genetically categorized as being either sporadic ALS (SALS) that represents 9095% of all diagnoses and in which there is no known direct genetic contribution to the disease, or familial ALS (FALS) that makes up the remaining 510% of all cases where known genetic mutations such as in SOD1, TDP-43, FUS, and C9ORF72 predominate (Zarei et al., 2015)