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A real-world JAMA Internal Medicine study of 18,386 propensity-matched patients found tirzepatide users were roughly twice as likely to hit 10%+ weight loss within a year
Additionally, heterogeneity among the SNPs was assessed using Cochranes Q test
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Contraindications for tirzepatide include hypersensitivity to the drug, personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, and severe gastrointestinal disease
1 Postulated mechanisms of medications used or being studied for treatment of hepatic encephalopathy
