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Abstract Introduction Glucagon-like peptide-1 (GLP-1) agonist and combined GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) agonist use has dramatically increased in recent years

Over time, while GLP-1 injections curbs our appetite and enhances feelings of fullness, this can lead to a reduction in food intake and ultimately contribute to weight loss

Meanwhile, dietary L-carnitine supplementation also inhibited glycolysis and enhanced gluconeogenesis to decrease glucose-derived energy production (Fig

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Constant hunger

Although there are medicinal treatments available for AUD, only about 2% of people with AUD use them