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Researchers at USC who first identified MOTS-C in 2015 called it an exercise mimetic because it triggers many of the same metabolic signals as a hard workout

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In contrast, our study confirmed decreased glutathione levels and increased ROS levels through BSO treatment or GCLC silencing, and revealed that while the depletion of glutathione did not compromise lymphoma cell survival in 2D culture, it sharply diminished viability in 3D gels

For 80%-90% of people with systemic mastocytosis, a mutation in the KIT gene is the cause

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