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When combined with GLP-1 agonism, glucagon receptor activation increases energy expenditure through thermogenesis, enhances fat oxidation and breakdown, improves metabolic rate in ways that counteract the metabolic slowdown typically accompanying weight loss, and may provide additional central appetite regulation

Strength training Incorporate muscle-strengthening exercises at least twice a week

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Phenylephrine overdose can cause a sudden spike in blood pressure, pounding headache, and irregular pulse

BMI, waist circumference, and waist-to-height ratio improved significantly with combination therapy

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