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Semaglutide is an injectable medication that mimics a natural hormone called GLP-1

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Rapid weight loss carries a risk of muscle wasting, known as sarcopenic obesity, if not managed correctly

Professor Linong Ji, the principal investigator of the study, Peking University People's Hospital, stated, "Accumulated evidence showed that Chinese people generally have higher percentages of body fat and higher rates of cardiovascular risk factors and all-cause mortality than western population at given BMI levels, therefore overweight and obesity in adults in China are defined with lower BMI cutoffs (overweight cutoff BMI 24 kg/m 2 , obesity cutoff BMI 28 kg/m 2 )

A systematic review with meta-analysis