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10.3389/fmolb.2022.925700 58 ZhaoY.LuanH.JiangH.XuY.WuX.ZhangY.et al (2021)
PMID 10833429
Add GIP receptor activation, as Tirzepatide does, and you layer in improved insulin sensitivity, enhanced fat metabolism, and what appears to be reduced GI side effects compared to GLP-1-only approaches
Evidence: The strongest data come from a large meta-analysis involving over 100,000 patients
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