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For context, diarrhoea is reported in approximately 916% of patients taking semaglutide 2.4 mg (Wegovy) according to its UK Summary of Product Characteristics (SmPC, emc), and in a broadly similar range for tirzepatide (Mounjaro) per its UK SmPC

Information supplied to pharmacists Initial limited supplies of GLP-1 therapies should be given to patients who cannot switch to other drug classes

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Both drug labels advise caution with alcohol

Some interesting data for obesity and emerging for MASH Many thanks to Ahmad Bahareth, MD for sharing Mazdutide: One of the Most Exciting Obesity Therapies to Watch in 2026 By Innovent Biologics Mazdutide (GLP-1/GCG dual receptor agonist) continues to build momentum with impressive clinical and regulatory achievements, positioning itself as a major competitor in the obesity and metabolic disease landscape

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