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[5] Two honest caveats sit on top of those numbers

It is worth mentioning that China's FDA said that the application for a marketing license for LIR injection for obesity or overweight indications had been accepted, which was the first time that the weight control indications of GLP-1R agonists have been accepted in China

26 , 686-698.e684

Specific clinical scenarios where injections are the standard of care include pernicious anemia, severe malabsorption syndromes, post-bariatric surgery when oral supplementation has failed, and critically low serum B12 levels accompanied by neurological deterioration

Wegovy dosing also starts at 0.25 mg weekly, but it can be increased to 2.5 mg weekly (3)

(35) Conclusion GLP-1 receptor agonists are becoming integral to obesity and diabetes management, with significant implications for orthopedic surgery