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Bibbiani F, Oh JD, Petzer JP, Castagnoli N Jr, Chen JF, Schwarzschild MA, et al

Remarkably, compromised mitochondrial function in ClpP IEC mice, as well as inhibition of mitochondrial respiration using oligomycin in murine and human organoid cultures was sufficient to reduce EEC marker gene expression, indicating a causative role for metabolism in steering differentiation into this IEC subtype

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