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In one case study, a woman with bipolar disorder felt an uncomfortable euphoria while taking semaglutide that resolved when she stopped the medication, suggesting that certain GLP-1s could impact mood in at least some individuals

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PlexusDx offers compounded semaglutide injection ($189/mo), tirzepatide options, and GLP-Squared dual-peptide formulations with no insurance required

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No human trial has characterized the side-effect profile of the blend specifically

Keep in mind that a true B12 deficiency usually requires correction under a doctor's guidance sometimes with injections or high-dose supplements along with a maintenance dose to keep levels up afterward