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Together, these results demonstrate that KG drives resistance to DNA-damaging agents

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Such a mechanism could theoretical be mediated by the oncoprotein MDM2, which interacts with p53 but has recently also been found to associate with certain cell surface receptors and regulate their functions (Shenoy et al, 2001)

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[P]atients with diabetes and obesity, which are the reasons for using GLP-1 medications often have existing risk factors for pancreatitis like gallstones, very high triglycerides, heavy alcohol use, or a history of pancreatitis