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Diabetes-related erectile dysfunction typically develops through several pathological mechanisms: Vascular damage from chronic hyperglycaemia, which impairs blood flow to penile tissues Autonomic neuropathy affecting the nerves responsible for initiating and maintaining erections Endothelial dysfunction , reducing the production of nitric oxide necessary for smooth muscle relaxation Hormonal imbalances , including reduced testosterone levels often associated with obesity When Ozempic improves glycaemic control, it may help slow or partially reverse some of these processes

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Mouse lymphoma model and tumor xenografts The previously described mouse model of Burkitt lymphoma C57BL/6N-Tg(IGL-MYC)3Hm (-MYC mice) [35] was obtained from the NCI mouse repository (Strain code 01XA7), backcrossed to C57BL/6J for more than 10 generations, and maintained in heterozygosity in a C57BL/6 J background

[5] Hagen TM et al