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Different GLP-1s should not be used at the same time

Tissue-specific expression of the human receptor for glucagon- like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences

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Researchers found that GLP-1 agonists used for weight loss were associated with increased risks of pancreatitis, gastroparesis, and bowel obstruction compared with bupropion-naltrexone, although that study should be understood as observational rather than definitive proof of causation

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