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J Clin Oncol 2002;20(16):3478-3483

Following that, the frequency changes based on your response

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What you might feel: Mild appetite reduction, sometimes barely noticeable Slight nausea in the first 24-48 hours after injection, typically resolving quickly Occasional changes in bowel habits Some people feel nothing at all, and that is completely normal at this dose What you should not feel: Severe nausea or vomiting (may indicate a dosing error, double-check your unit calculation ) Complete loss of appetite (unusual at 2.5 mg) Significant weight loss (possible but not typical at the initiation dose) Do not increase your dose before completing four full weeks at 2.5 mg