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Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide
Novel and adjunctive antioxidant therapies N-acetylcysteine (NAC) NAC, a potent thiol-containing antioxidant, has garnered increasing attention for its therapeutic potential in mitigating the pathophysiological consequences of sepsis, particularly through modulation of oxidative stress and inflammation
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